Isotopically Labeled Compounds
Medchemexpress LLC Succinimide-15N | 32807-36-6 | 99.0% | 100.08 | 25 MG
Succinimide-15N is the 15N labeled Succinimide. Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. It is utilized in the development of antiepileptic agents.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Ethosuximide-d3 | 1189703-33-0 | ≥99.0% | 1 MG
Ethosuximide-d3 is the deuterium labeled Ethosuximide. It is a widely prescribed anti-epileptic agent that improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled ethosuximide.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Improves phenotypes of multiple neurodegenerative disease models.
- Blocks low voltage activated T-type calcium channel.
- Deuterium substitution can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sulbactam-d5 sodium | 1322625-44-4 | 99.9% | 500 UG
Sulbactam-d5 sodium is a deuterium-labeled form of Sulbactam sodium, a competitive, irreversible beta-lactamase inhibitor. It demonstrates antimicrobial activity against multidrug-resistant Acinetobacter calcoaceticus--Acinetobacter baumannii complex. Deuteration in drug molecules can impact pharmacokinetic and metabolic profiles, making this compound valuable for research.
- Functions as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Isotope-labeled compound
- Deuterium stable isotope-labeled inhibitor for in vivo cell experiments
- Applicable in therapeutic drug monitoring
Medchemexpress LLC Acetamide, N-[4-(ethoxy-d5)phenyl]- | 69323-74-6 | 99.5% | 50 MG
Phenacetin-d5 is a deuterium-labeled form of Phenacetin, a non-opioid analgesic and antipyretic agent. It functions as a selective COX-3 inhibitor and is utilized as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats.
- Deuterium-labeled Phenacetin
- Non-opioid analgesic and antipyretic
- Selective COX-3 inhibitor
- Used as a probe for cytochrome P450 enzymes CYP1A2
Medchemexpress LLC Ketoprofen-d4 | 1219805-29-4 | 98.7% | 1 MG
Ketoprofen-d4 (RP-19583-d4) is a deuterium-labeled derivative of Ketoprofen, a non-steroidal anti-inflammatory agent (NSAID). This compound acts as a potent inhibitor of cyclooxygenase (COX) enzymes, with reported IC50 values of 2 nM for COX-1 and 26 nM for COX-2 in human blood monocytes. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs. Ketoprofen-d4 is suitable for use as a tracer in research applications and as an internal standard for quantitative analysis.
- Potent inhibitor of cyclooxygenase enzymes
- Suitable for use as a tracer in research applications
- Ideal as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotope
- Highly soluble in DMSO
Medchemexpress LLC Lapatinib-d4 | 1184263-99-7 | 99.0% | 585.08 | C29H22D4ClFN4O4S | 10 MG
Lapatinib-d4 is the deuterium-labeled isotopologue of lapatinib used as a stable isotope standard for analytical and pharmacokinetic studies. It is supplied as a solid powder in pre-weighed quantities with specified storage recommendations for long-term stability.
- Deuterium-labeled internal standard for LC-MS/MS assays.
- High purity (≈99%) suitable for quantitative analysis.
- Offered in small pre-weighed amounts for method development.
- Stable in powder form under low-temperature storage.
- Comes with a product datasheet and safety data sheet for handling.
Medchemexpress LLC Α-Vitamin E-d6 | 113892-08-3 | 5 MG
α-Vitamin E-d6 is a deuterium-labeled form of α-Vitamin E, intended for research use only. This compound serves as a tracer and internal standard for quantitative analysis via methods like NMR, GC-MS, or LC-MS. Incorporating stable heavy isotopes such as deuterium can influence the pharmacokinetic and metabolic profiles of drugs during development. It has a molecular weight of 436.74, a chemical formula of C29H44D6O2, and appears as a light yellow to yellow oil with a purity of 98.85%.
- Used as a tracer
- Functions as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Deuterium labeling can impact pharmacokinetic and metabolic profiles
Medchemexpress LLC p-Toluic acid-d3 | 19215-16-8 | >98.0% | 139.17 g/mol | C8H5D3O2 | 10 MG
p-Toluic acid-d3 (4-methylbenzoic acid-d3) is the deuterium-labeled form of p-toluic acid, intended for analytical and synthetic use. It is used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS, and as an intermediate in organic synthesis.
- Used as an internal standard for NMR, GC-MS, and LC-MS quantitative analysis.
- Suitable as a synthetic intermediate for organic chemistry applications.
- Available in small-scale quantities for analytical use, e.g., 10 MG.
- Chemical purity min 98% with isotopic enrichment typically 98 atom % D.
Medchemexpress LLC D-Fructose-13C2 | 2483736-14-5 | 10 MG
D-Fructose-13C2 is the 13C labeled form of D-Fructose, a naturally occurring monosaccharide found in many plants. This compound serves as a valuable tool for research, particularly as a tracer and an internal standard in various analytical techniques.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 2,4(1H,3H)-pyrimidinedione-5,6-d2 | 24897-52-7 | 99.9% | 114.10 | C4H2D2N2O2 | 10 MG
Uracil-d2 is the deuterium-labeled analogue of uracil, used as an isotopic standard and tracer in analytical and metabolic studies. It is a white to off-white solid with molecular formula C4H2D2N2O2 and CAS number 24897-52-7.
- Deuterium-labeled for mass spectrometry tracing and isotopic studies.
- High reported purity (≈99.9%).
- Suitable as an internal standard for quantitative assays.
- Supplied in small research quantities appropriate for analytical applications.
- Stable as a powder with recommended cold storage to preserve isotopic integrity.
Medchemexpress LLC L-(-)-xylose-2-13C | 478506-63-7 | 99.0% | 151.12 | C5H10O5 (13C at 2-position) | 10 MG
L-Xylose-2-13C is the 13C-labeled form of L-xylose used as an isotopically labeled standard or tracer in analytical and synthetic applications. It is suitable for use as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS, and as a raw material for synthesis of bioactive molecules.
- Isotopically labeled at the 2-position for precise tracer studies.
- High purity suitable for analytical applications.
- Available in small pack sizes for method development and standards.
- Solid, white to off-white appearance for easy handling.
Medchemexpress LLC Levosulpiride-d3 | 124020-27-5 | 99.8% | 1 MG
Levosulpiride-d3 is the deuterium labeled Levosulpiride, an (S)-enantiomer of sulpiride that acts as a D2 receptor antagonist and atypical antipsychotic agent of the benzamide class. This compound is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC Nonadecane | 629-92-5 | 100 MG
Nonadecane is a herbicide used for the control of weeds in Dendrobium orchids. This product is provided as a colorless to off-white solid.
- Purity: 98.0%
- Molecular weight: 268.52
- Chemical formula: C19H40
- Appearance: Solid
- Color: Colorless to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Solubility in ethanol: 20 mg/mL (74.48 mM)